Adapalene is a retinoid medication commonly used for acne treatment. While there is limited research on its safety during pregnancy, it is generally recommended to avoid using retinoids during this time due to potential risks. Adapalene can be absorbed into the bloodstream and may pose a risk of birth defects or harm to the developing fetus. It is important to consult with your healthcare provider before using any medications, including topical gels, while pregnant. They can assess your individual situation and provide guidance based on your specific needs. In some cases, alternative treatments or skincare routines may be recommended that are safer for use during pregnancy.